The resistance and hesitancy towards vaccination guidelines - suggested, or sometimes imposed, by state health systems - is not a widespread phenomenon that began in the Internet age. Instead, this outlook was already present in the complex history of the previous centuries of medical institutions and state, political and health decisions, official communications and popular beliefs. This article helps to frame and discuss some of the elements underlying the "bottom-up" processing of biomedicine rejection: social and individualistic drives, information and science sharing issues.